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jobBroad InstituteJune 29, 2026

Computational Scientist I – McCarroll Lab

The McCarroll Lab at the Broad Institute seeks a computational scientist to develop and optimize analysis methods for single-cell RNA-seq, ATAC-seq, and multiome datasets studying genetic and neurobiological factors in brain disorders. The role involves building analytical tools, creating data visualizations, and developing optimal workflows for high-data-volume experiments in close collaboration with scientists and software engineers across the Broad and Harvard Medical School. Salary $88,000–$124,000; Cambridge, MA (Hybrid); posted June 23, 2026.

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Computational Scientist I – McCarroll Lab

Location: Cambridge, MA (Hybrid)  |  Salary: $88,000–$124,000  |  Ref: 44407  |  Posted: June 23, 2026

The Broad Institute seeks a computational scientist to support the McCarroll Lab's research on genetic and neurobiological factors in brain disorders, working closely with scientists, project and data managers, and software engineers across the Broad Institute and Harvard Medical School.

Key Responsibilities

  • Develop and optimize analysis methods for single-cell RNA-seq, ATAC-seq, and multiome datasets
  • Conduct data analysis addressing disease pathogenesis, genetics, and biomarkers
  • Build new analytical tools with thorough code documentation
  • Create data visualizations for internal and external audiences
  • Develop optimal analysis workflows for high-data-volume experiments

Required Qualifications

  • PhD in Computer Science, Mathematics, Statistics, Biology, Bioinformatics, or related field
  • 2+ years direct work experience
  • Proficiency in Python and/or R
  • Experience analyzing next-generation sequencing data, preferably single-cell RNA-seq
  • Knowledge of data science principles